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Rash :: PLAB 2 Symptomatic Differential Stations

  • Suspected malignant melanoma

    • Other presenting symptoms 

      • Sometimes itching with a tingling sensation. 

      • Irregular colour

      • Sometimes bleeds. 

      • No pain. 

      • Growing in size 

      • Sun exposure/ tanning

      • FLAWS

    • Past history and PMAFTOSA Rule out FLAWS, suicidal thoughts

    • Social 

    • Exam and Invs

      • GPE, vitals,

      • Lesion exam

      • Head-to-toe exam

      • Biopsy

    • Referral Dermatologist

    • Treatment 

    • Warning signs

      • Symptoms getting worse

  • Cellulitis after Insect bite 

    • Other presenting symptoms 

      • Increasing pain and size

      • Fever

    • Past history and PMAFTOSA

    • Social 

    • Exam and Invs

      • GPE, vitals,

      • Lesion exam

      • Head-to-toe exam

    • Referral Medicine admission

    • Treatment 

      • Painkiller

      • IV antibiotics

    • Warning signs

      • Feeling faint, dizziness

  • Lyme disease

    • Other presenting symptoms 

      • Round/oval, bulls-eye appearance with incomplete central clearing and central punctum

      • Increasing pain and size

      • Bleeding, itching, pain, pus/discharge/oozing, blistering.

      • Fever, night sweats

      • Flu-like illness

    • Past history and PMAFTOSA

      • Bitten by a tick, recently visited woodland / grassy area in the UK or abroad

    • Social 

    • Exam and Invs

      • GPE, vitals,

      • Lesion exam

      • Head-to-toe exam

    • Referral Infectious diseases

    • Treatment 

      • Painkiller, paracetamol

      • Doxycyclin for 21 days (start ASAP before referral)

    • Warning signs

      • Slight worsening of symptoms initially after starting treatment (Jarisch-Herxheimer reaction (reaction to the dying bacteria) - expected) but come back to the hospital if becomes too much.

      • General measures about tick safety and check other family members for tick bites as well.

  • Chickenpox in a 3-year-old

    • Other presenting symptoms

      • Vesicles (fluid-filled)

      • Starts on the face and then spreads to the rest of the body. 

      • Fever, cough, and runny nose. 

    • Past history and PMAFTOSA

      • Pregnancy and birth history

      • Vaccination and development history

    • Social-


    • Exam and Invs

      • GPE, vitals,

      • Lesion exam

      • Head-to-toe exam

    • Referral 

      • None

    • Treatment 

      • Paracetamol, antihistamines

      • Self-limiting

      • General measures (no scratching, loose clothes, avoid contact with others, plenty of fluids)

    • Warning signs

      • Signs of bacterial infection (high fever, redness/swelling around the vesicles)

  • Measles in 25yr old student (404) 

    • Other presenting symptoms

      • Starts behind the ear then spread to the rest of the body. 

      • Fever, cough, and runny nose.

      • MMR vaccine not taken/ not sure

    • Past history and PMAFTOSA


    • Social-


    • Exam and Invs

      • GPE, vitals

      • Lesion exam

      • Head-to-toe exam

    • Referral 

      • Notify Health Protection Team

    • Treatment 

      • Self-limiting

      • Symptomatic management

    • Warning signs

      • Avoid contact with immunosuppressed people and others

      • MMR vaccine once recovered

      • Symptoms not resolved in a week.

      • Shortness of breath, uncontrolled fever

      • Convulsions, or altered consciousness

  • Impetigo

    • Other presenting symptoms

      • Honey-crusted blisters/lesions around mouth

      • No pain, no itch

    • Past history and PMAFTOSA

      • Sexual history

    • Social-

      • Confidence and self esteem

      • Psychological issues

    • Exam and Invs

      • GPE, vitals

      • Lesion examination

      • Head-to-toe examination

    • Referral 

      • None

    • Treatment 

      • Fusidic acid topical 2-3 times a day

      • General measures

        • Avoid scratching

        • Hygiene

        • Very contagious 

        • Avoid sex, contact

    • Warning signs

      • Fever, increasing lesions 

  • Syphilis

    • Other presenting symptoms

      • Rash on genital area (single, painless)

      • Dysuria

      • Groin swelling

      • Lymph node enlargement

      • Fever

    • Past history and PMAFTOSA

      • Sexual history

    • Social


    • Exam and Invs

      • GPE, vitals

      • General examination

      • Groin examination

      • LN examination

      • Chest examination

      • Lesion swab

      • Screening for other STIs (offer)

    • Referral 

      • GUM clinic

    • Treatment 

      • Antibiotics

      • Avoid sex till treatment complete

      • Safe sex

      • Partner notification program

    • Warning signs

      • Headache, dizziness, chest pain, SOB

  • Genital warts

    • Other presenting symptoms

      • Multiple painless swellings

    • Past history and PMAFTOSA

      • Sexual history

    • Social-


    • Exam and Invs

      • GPE, vitals

      • General examination

      • Groin examination

      • LN examination

    • Referral 

      • GUM clinic

    • Treatment 

      • Topical cream

      • cryotherapy/excision

    • Warning signs

      • Discharge, Pain, fever

  • Genital herpes

    • Other presenting symptoms

      • Multiple painful ulcers

      • Dysuria, discharge

      • Fever, flu-like illness

    • Past history and PMAFTOSA

      • Sexual history

      • Pregnancy history (Important)

    • Social-


    • Exam and Invs

      • GPE, vitals

      • General examination

      • Groin examination

      • LN examination

    • Referral 

      • GUM clinic

    • Treatment 

      • Painkillers

      • Topical anaesthesia

      • Plenty of fluids

      • Acyclovir in immunocompromised and in pregnancy 

    • Warning signs

      • Avoid sex till treatment complete

      • Safe sex

      • Partner notification program

  • Herpetic Whitlow

    • Other presenting symptoms

      • No history of injury.

      • Current or recent oral or genital herpetic lesions (e.g. cold sores)

      • pain and paraesthesia of the affected finger.

      • oedema, redness, and localized tenderness of the infected finger 

      • A previous history of herpetic whitlow 

      • Presence of vesicles or blisters.

    • Past history and PMAFTOSA

      • Immunocompromised?

      • Sexual history

    • Social-


    • Exam and Invs

      • GPE, vitals

      • Finger examination

      • Groin examination if any ulcers

    • Referral 

      • None

    • Treatment 

      • Acyclovir if presented within 48 hours of onset

    • Warning signs

      • Infection gets worse or develops fever

  • Intertrigo

    • Other presenting symptoms

      • Uniformly red without central clearing or scale

      • Under both breasts

      • mechanical causes (moisture, friction, heat), 

      • commonly associated with superimposed infection (candida or bacterial).

    • Past history and PMAFTOSA


    • Social-

      • Confidence and self esteem

      • Psychological issues

    • Exam and Invs

      • GPE, vitals

      • Breast examination

      • Head-to-toe examination

    • Referral 

      • none

    • Treatment 

      • Clotrimazole cream

      • Hydrocortisone cream

      • General measures

        • Avoid scratching

        • Hygiene

        • Loose clothes

    • Warning signs

      • Follow up after 7 days if not improved

      • Fever, feeling unwell

  • Psoriasis

    • Other presenting symptoms

      • Distribution - symmetrical, extensor surfaces (elbows and knees), trunk, flexures, sacral and natal cleft, scalp and behind the ears, and umbilicus.

      • Silvery Scales

      • joints or nail involvement

      • Auspitz's sign - if the scale is gently removed, a glossy red membrane with pinpoint bleeding points is revealed.

      • Triggers - stress, smoking, alcohol, infections, drugs (including steroid withdrawal), UV light exposure, injury to skin, hormonal changes

    • Past history and PMAFTOSA


    • Social-

      • Confidence and self esteem

      • Psychological issues

    • Exam and Invs

      • GPE, vitals

      • Lesion examination

      • Head-to-toe examination

    • Referral 

      • Dermatology routine

    • Treatment 

      • Symptomatic treatment

        • Emollients

        • Steroid and Vitamin D preparations

        • Smoking cessation

        • Stress management

    • Warning signs

      • Joint involvement (psoriatic arthritis)

      • Steroid side effects

  • Eczema in a 15 yr old

    • Other presenting symptoms

      • Flexor aspects 

      • History of asthma usually

    • Past history and PMAFTOSA

      • Asthma

      • Previous similar episodes

    • Social-

      • Confidence and self esteem

      • Psychological issues

    • Exam and Invs

      • GPE, vitals

      • Lesion examination

      • Head-to-toe examination

    • Referral 


    • Treatment 

      • Emollients

      • General measures

    • Warning signs

      • Swelling of the face, wheeze

      • psychological issues

      • any redness, oozing and crusting of the skin, high fever (bacterial infection)

  • Molloscum Contagiosum 

    • Other presenting symptoms

      • Dome-shaped, central depression (umbilication), trunk and folds (knee, armpit, groin)

    • Past history and PMAFTOSA

      • contact history.

    • Social-

      • Confidence and self esteem

      • Psychological issues

    • Exam and Invs

      • GPE, vitals

      • Lesion examination

      • Head-to-toe examination

    • Referral 

      • None

    • Treatment 

      • Self-limiting

      • General measures:

        • Keep dry

        • Avoid contact

        • Avoid scratching

    • Warning signs

      • Increasing or painful 

  • Erythema Nodosum

    • Other presenting symptoms

      • Painful, red, hot nodules and plaques on the shins/knees/ankles,

      • Symmetrical, not well demarcated, typically 15-45 years old

      • Common causes (idiopathic, streptococcal infections, sarcoidosis, medications: antibiotics / NSAIDs / COCP, pregnancy, IBD).


  • Past history and PMAFTOSA


  • Social-

    • Confidence and self esteem

    • Psychological issues

  • Exam and Invs

    • GPE, vitals

    • Lesion examination

    • CVS, RS, CNS, abdomen examination

    • Routine bloods

    • Calcium/ACE level (sarcoid)

    • ASO titre, throat culture (strep)

    • CXR (sarcoid, TB, mycoplasma)

    • Fecal calprotectin (IBD)

  • Referral 

    • Specialist if not idiopathic

  • Treatment 

    • Self-limiting if idiopathic

  • Warning signs

    • Follow up with results in 1-2 weeks

    • Fever, cough

    • Increasing nodules or pain

    • Bowel symptoms

  • Folliculitis

    • Other presenting symptoms

      • Clusters of red/yellow pimples

      • Recent wax/shaving history

    • Past history and PMAFTOSA

      • Sexual history

    • Social-

      • Confidence and self esteem

      • Psychological issues

    • Exam and Invs

      • GPE, vitals

      • Lesion examination

      • Groin examination

      • Inguinal lymph node examination

    • Referral 

      • None

    • Treatment 

      • Emollients

      • Hygiene

      • Self-care measures

        • Clean razor

        • Apply after-shave

        • Lubricate skin when shaving

    • Warning signs

      • Increasing pain, number or high fever

  • Cat Bite

    • Other presenting symptoms


    • Past history and PMAFTOSA

      • Vaccination history:

        • Tetanus 

        • Rabies

    • Social-


    • Exam and Invs

      • GPE, vitals 

      • Lesion examination

      • Head-to-toe examination

    • Referral 

      • None

    • Treatment 

      • Pain relief

      • Clean wound

      • Tetanus (if not given within last 10 years)

      • Rabies (ask senior)

      • Co-amoxiclav for 3 days

    • Warning signs

      • Signs of infection

  • Ringworm

    • Other presenting symptoms

      • Itchy, red, round lesion

      • Contact history might be there

    • Past history and PMAFTOSA


    • Social-

      • Confidence and self esteem

      • Psychological issues

    • Exam and Invs

      • GPE, vitals

    • Referral 

      • none

    • Treatment 

      • Topical antifungal cream (clotrimazole)

      • General measures:

        • Keep dry

        • Avoid contact

        • Avoid scratching

    • Warning signs

      • Fever, worsening symptoms

  • Heat-related Urticaria 

    • Other presenting symptoms

      • Pinkish rash

      • Itchy

      • Trigger (Hot shower/Sun exposure)

    • Past history and PMAFTOSA

      • Atopy/allergy history

      • Vaccination history

    • Social-


    • Exam and Invs

      • GPE, vitals

      • Lesion examination

      • Head-to-toe examination

    • Referral 

      • None

    • Treatment 

      • Self-limiting

      • Rash diary for triggers

    • Warning signs

      • Fever, swelling of the face, wheeze

  • Scabies in 5yr old (343) | 

    • Other presenting symptoms

      • Rash between fingers

      • Recent camping history

    • Past history and PMAFTOSA

      • Atopy/allergy history

      • Vaccination history

    • Social-


    • Exam and Invs

      • GPE, vitals

      • Lesion examination

      • Head-to-toe examination

    • Referral 

      • None

    • Treatment 

      • 5% permethrin

        • Apply on whole body

        • Dont apply after a hot bath

        • Allow cream to dry before putting on clothes

      • Treat all household members and contacts even if asymptomatic

      • Decontaminate bedding and stuff

    • Warning signs

      • If itching lasts longer than 4 weeks

      • High fever

  • Ingrown toenail / acute paronychia (infected ingrown toenail)

    • Other presenting symptoms

      • Big toe commonly involved

      • Trauma/tight shoes/improper grooming

      • Pus maybe present if paronychia

    • Past history and PMAFTOSA

      • Rule out Gout history (previous episodes/ alcohol history/ family history)

      • Rule out diabetes (can worsen if has diabetic neuropathy)

    • Social-


    • Exam and Invs

      • GPE, vitals

      • Lesion examination

      • Head-to-toe examination

    • Referral 

      • Podiatrist if badly ingrown toenail

    • Treatment 

      • Self-care measures

        • Hygiene

        • Proper technique of cutting toenails

      • Topical/Oral antibiotics if paronychia

    • Warning signs

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