NewCase_8: Treponema Pallidum Test
- Ann Augustin
- Nov 6, 2024
- 6 min read
Updated: Nov 7, 2024

Question 1: In which of the following situations is a Treponema pallidum test indicated?
A. A patient presenting with a painless genital sore.
B. Routine screening for all teenagers.
C. A patient with a rash on the palms and soles of the feet.
D) A patient with severe headaches and vision problems.
Answers:
A, C, D
Explanation:
A. A patient presenting with a painless genital sore.Correct. A painless sore, known as a chancre, is a classic sign of primary syphilis.
B. Routine screening for all teenagers.Incorrect. Routine syphilis testing isn't indicated for all teenagers without specific risk factors.
C. A patient with a rash on the palms and soles of the feet.Correct. This type of rash is characteristic of secondary syphilis.
D. A patient with severe headaches and vision problems.Correct. These symptoms can indicate neurosyphilis, a serious complication.
E. A patient with a common cold.Incorrect. Common cold symptoms are unrelated to syphilis.
Question 2: How and when is the Treponema pallidum test performed?
A. By taking a blood sample to detect antibodies.
B. Only if the patient shows visible symptoms.
C. Using a swab from a sore for direct detection.
D. It requires the patient to fast overnight.
Answers:
A, C
Explanation:
A. By taking a blood sample to detect antibodies.Correct. Blood tests are commonly used to detect antibodies against syphilis.
B. Only if the patient shows visible symptoms.Incorrect. Testing can be done even without symptoms, especially if exposure is suspected.
C. Using a swab from a sore for direct detection.Correct. A sample from a chancre can be examined for the presence of Treponema pallidum.
D. It requires the patient to fast overnight.Incorrect. Fasting is not necessary for syphilis testing.
E. It can provide results within minutes at the clinic. Incorrect. Syphilis tests usually require laboratory analysis and are not instant.
Question 3: What are common patient complaints that may lead to ordering a Treponema pallidum test?
A. Painless genital ulcers.
B. Sore throat and runny nose.
C. Unexplained fever and fatigue.
D. Swollen lymph nodes.
Answers:
A, C, D
Explanation:
A. Painless genital ulcers.Correct. Chancres are painless ulcers indicative of primary syphilis.
B. Sore throat and runny nose.Incorrect. These are common cold symptoms, not specific to syphilis.
C. Unexplained fever and fatigue.Correct. These are systemic symptoms that can occur in secondary syphilis.
D. Swollen lymph nodes.Correct. Lymphadenopathy is common in syphilis.
E. Joint pain in multiple areas. Incorrect. While possible, joint pain is less specific and not a primary symptom.
Question 4: Which additional tests are often performed alongside the Treponema pallidum test?
A. HIV test.
B. Complete blood count (CBC).
C. Hepatitis B and C screening.
D. Urinalysis.
Answers:
A, C, E
Explanation:
A. HIV test.Correct. Due to similar transmission routes, co-testing is important.
B. Complete blood count (CBC).Incorrect. Not routinely performed specifically for syphilis but may be part of general assessment.
C. Hepatitis B and C screening.Correct. These infections share risk factors with syphilis.
D. Urinalysis.Incorrect. Not specific to syphilis testing.
E. Chlamydia and gonorrhea tests.Correct. These STIs often coexist with syphilis.
Question 5: What is the recommended follow-up after a positive Treponema pallidum test?
A. Begin treatment immediately with antibiotics.
B. No need to inform sexual partners.
C) Schedule blood tests to monitor treatment.
D) Take a single dose with no further review.
Answers:
A, C, E
Explanation:
A. Begin treatment immediately with antibiotics.Correct. Prompt treatment is essential to prevent complications.
B. No need to inform sexual partners.Incorrect. Sexual partners should be notified for testing and treatment.
C. Schedule blood tests to monitor treatment.Correct. Follow-up tests ensure the infection is cleared.
D. Take a single dose with no further review.Incorrect. Follow-up is necessary to confirm treatment success.
E. Abstain from sexual activity until cleared by a doctor. Correct. Prevents transmission to others.
Question 6: What lifestyle modifications should be advised after a syphilis diagnosis?
A. Practice safe sex using condoms.
B. Limit alcohol and tobacco use.
C. Maintain a healthy diet to boost immunity.
D. Avoid all physical activity.
Answers:
A, B, C
Explanation:
A. Practice safe sex using condoms.Correct. Reduces risk of transmission and reinfection.
B. Limit alcohol and tobacco use.Correct. Supports overall health and immune response.
C. Maintain a healthy diet to boost immunity.Correct. Aids in recovery and general well-being.
D. Avoid all physical activity.Incorrect. Physical activity is generally safe unless otherwise advised.
E. Get vaccinated against syphilis. Incorrect. There is currently no vaccine for syphilis.
Question 7: What safety netting advice should be provided to prevent further worsening?
A. Report any new or worsening symptoms immediately.
B. Resume sexual activity immediately after starting tx.
C. Complete the full course of prescribed antibiotics.
D. You can donate blood after treatment begins.
Answers:
A, C, E
Explanation:
A. Report any new or worsening symptoms immediately.Correct. Early reporting can prevent complications.
B. Resume sexual activity immediately after starting tx. Incorrect. Sexual activity should be avoided until cleared.
C. Complete the full course of prescribed antibiotics.Correct. Ensures effective treatment.
D. You can donate blood after treatment begins.Incorrect. Blood donation is deferred until confirmed cure.
E. Attend all scheduled follow-up appointments.nCorrect. Critical for monitoring recovery.
Question 8: How would you explain the Treponema pallidum test in layman's terms?
A. It's a blood test to see if you have syphilis, a STI.
B. We check your blood sugar levels with this test.
C. This test tells us if you have any kind of infection.
D. It's a routine test everyone needs annually.
Answers:
A, E
Explanation:
A. It's a blood test to see if you have syphilis, a STI.Correct. Provides a clear and simple explanation.
B. We check your blood sugar levels with this test.Incorrect. Unrelated to syphilis testing.
C. This test tells us if you have any kind of infection.Incorrect. The test is specific to syphilis.
D. It's a routine test everyone needs annually.Incorrect. Not routinely done for everyone.
E.We look for specific signs of syphilis-causing bacteria. Correct. Explains the purpose of the test.
Question 9: In the NHS, where is the Treponema pallidum (syphilis) test typically performed?
A. At a Sexual Health Clinic (GUM clinic)
B. In any hospital's emergency department
C. At the patient's home by a mobile testing unit
D. In general practice (GP) surgeries
Answers:
A, D
Explanation:
A. At a Sexual Health Clinic (GUM clinic)Correct. These clinics specialize in testing and treating STIs.
B. In any hospital's emergency departmentIncorrect. Not routinely performed in emergency settings.
C. At the patient's home by a mobile testing unitIncorrect. Home testing is not standard for syphilis in the NHS.
D. In general practice (GP) surgeriesCorrect. GPs can order tests and collect samples.
E. Only at specialist infectious disease hospitals. Incorrect. Testing is widely available, not restricted to specialist centers.
Question 10: Who is responsible for ordering a Treponema pallidum test in the NHS?
A. Any healthcare professional without patient consent
B. General Practitioners (GPs)
C. Sexual health specialists
D. Patients can self-refer at sexual health clinics
Answers:
B, C, D
Explanation:
A. Any healthcare professional without patient consentIncorrect. Patient consent is required for testing.
B. General Practitioners (GPs)Correct. GPs can order the test based on clinical need.
C. Sexual health specialistsCorrect. Specialists in GUM clinics can perform testing.
D. Patients can self-refer at sexual health clinicsCorrect. Patients may attend without a referral.
E. Pharmacists. Incorrect. Pharmacists do not order syphilis tests.
Question 11: What is the first-line treatment for early syphilis infection?
A. Oral doxycycline for 14 days
B. A single IM injection of benzathine benzylpenicillin
C. Oral azithromycin
D. Topical antibiotics applied to sores
Answers:
A, B
Explanation:
A. Oral doxycycline for 14 daysCorrect. An alternative for patients allergic to penicillin.
B. A single IM injection of benzathine benzylpenicillinCorrect. The standard first-line treatment.
C. Oral azithromycinIncorrect. Not recommended due to resistance concerns.
D. Topical antibiotics applied to soresIncorrect. Systemic treatment is required.
E. No treatment; it resolves on its own. Incorrect. Syphilis requires medical treatment to prevent complications.
Question 12: When should a patient with syphilis be referred to a specialist?
A. If they are pregnant
B. If they have signs of neurosyphilis
C. Only after completing initial treatment
D. If they are allergic to penicillin
Answers:
A, B, D
Explanation:
A. If they are pregnantCorrect. Specialist care ensures proper management to prevent congenital syphilis.
B. If they have signs of neurosyphilisCorrect. Requires specialist evaluation and treatment.
C. Only after completing initial treatmentIncorrect. Early referral is important in certain cases.
D. If they are allergic to penicillinCorrect. To explore alternative treatments or desensitization.
E. Referral is not necessaryIncorrect. Referral may be crucial depending on the situation.
Question 13: Which follow-up actions are recommended after syphilis treatment?
A. No follow-up is needed after treatment
B. Repeat blood tests at 3, 6, and 12 months
C. Sexual partners should be notified and tested
D. Abstain from sexual activity for at least 2 wks after tx
Answers:
B, C, D
Explanation:
A. No follow-up is needed after treatmentIncorrect. Follow-up testing is essential.
B. Repeat blood tests at 3, 6, and 12 monthsCorrect. To confirm treatment success and monitor for reinfection.
C. Sexual partners should be notified and testedCorrect. Helps prevent further spread.
D. Abstain from sexual activity for at least 2 wks after txCorrect. Reduces risk of transmission until non-infectious.
E. Once treated, no further precautions are necessary. Incorrect. Ongoing safe practices are important.
Question 14: What are possible complications if syphilis is left untreated?
A. Cardiovascular problems affecting the heart
B. Permanent joint damage leading to arthritis
C. Blindness due to eye involvement
D. Mental deterioration and neurological issues
Answers:
A, C, D
Explanation:
A. Cardiovascular problems affecting the heartCorrect. Late syphilis can cause aortic aneurysm and valve disease.
B. Permanent joint damage leading to arthritisIncorrect. Not a typical complication of syphilis.
C. Blindness due to eye involvement. Correct. Ocular syphilis can lead to vision loss.
D. Mental deterioration and neurological issuesCorrect. Neurosyphilis can cause severe neurological deficits.
E. Kidney failure. Incorrect. Kidney involvement is not a common complication.
Question 15: Which patients should be routinely offered syphilis testing in the NHS?
A. Pregnant women during antenatal care
B. Individuals diagnosed with another STI
C. People with multiple sexual partners
D. All patients visiting their GP
Answers:
A, B, C, E
Explanation:
A. Pregnant women during antenatal careCorrect. To prevent congenital syphilis transmission.
B. Individuals diagnosed with another STICorrect. High-risk group for co-infections.
C. People with multiple sexual partnersCorrect. Increased risk warrants testing.
D. All patients visiting their GPIncorrect. Testing is based on risk assessment.
E. Blood donors. Correct. Blood is screened for syphilis to ensure safety.
Question 16: Which of the following are essential points in patient education about syphilis?
A. Syphilis is transmitted through unprotected sex
B. Syphilis is not curable
C. Informing sexual partners is crucial
D. Symptoms may vanish without tx, but the disease persists.
Answers:
A, C, D
Explanation:
A. Syphilis is transmitted through unprotected sexCorrect. Key information for prevention.
B. Syphilis is not curableIncorrect. Syphilis is curable with appropriate antibiotics.
C. Informing sexual partners is crucialCorrect. To prevent spread and allow partners to seek treatment.
D. Symptoms may vanish without tx, but the disease persists.Correct. Syphilis can become latent and still cause damage.
E. Once treated, reinfection is not possible. Incorrect. Reinfection can occur if exposed again.
Question 17: What precautions should healthcare workers take when handling specimens for syphilis testing?
A. Wear gloves when collecting blood samples
B. Use standard infection control precautions
C. No special precautions are needed
D. Dispose of needles safely in sharps containers
Answers:
A, B, D, E
Explanation:
A. Wear gloves when collecting blood samplesCorrect. Protects both patient and healthcare worker.
B. Use standard infection control precautionsCorrect. Minimizes risk of cross-infection.
C. No special precautions are neededIncorrect. Standard precautions are always necessary.
D. Dispose of needles safely in sharps containersCorrect. Prevents needle-stick injuries.
E. Sterilize equipment between patients. Correct. Essential to prevent contamination.
Question 18: Which medications are safe alternatives for treating syphilis in patients allergic to penicillin?
A. Oral doxycycline
B. Intravenous ceftriaxone
C. Oral erythromycin
D. Topical acyclovir cream
Answers:
A, B
Explanation:
A. Oral doxycyclineCorrect. Effective alternative for non-pregnant patients.
B. Intravenous ceftriaxoneCorrect. Used in certain cases, especially neurosyphilis.
C. Oral erythromycinIncorrect. Less effective and not preferred.
D. Topical acyclovir creamIncorrect. Used for herpes simplex virus, not syphilis.
E. Oral metronidazole. Incorrect. Treats anaerobic bacterial infections, not syphilis.
Question 19: What steps should be taken if a patient diagnosed with syphilis is pregnant?
A. Immediate referral to obstetric care
B. Delay treatment until after childbirth
C. Administer penicillin regardless of allergy status
D. Monitor the baby after birth for congenital syphilis
Answers:
A, C, D
Explanation:
A. Immediate referral to obstetric careCorrect. Ensures appropriate management of mother and fetus.
B. Delay treatment until after childbirthIncorrect. Early treatment is critical to prevent fetal infection.
C. Administer penicillin regardless of allergy statusCorrect. Penicillin is the only proven effective treatment; desensitization may be necessary.
D. Monitor the baby after birth for congenital syphilisCorrect. Early detection and treatment improve outcomes.
E. Terminate the pregnancy. Incorrect. Not a standard recommendation; management focuses on treatment.
Question 20: How is the Treponema pallidum test explained to patients in simple terms?
A. It's a blood test to check for syphilis, a STI.
B. We measure your cholesterol levels with this test
C. This test detects the germ that causes syphilis.
D. It's a routine test everyone gets during a check-up
Answers:
A, C
Explanation:
A. It's a blood test to check for syphilis, a STI.Correct. Provides a straightforward explanation.
B. We measure your cholesterol levels with this testIncorrect. Unrelated to syphilis testing.
C. This test detects the germ that causes syphilis.Correct. Explains that the test detects the bacteria itself.
D. It's a routine test everyone gets during a check-upIncorrect. Not routinely performed without indications.
E. We test your urine for signs of infection. Incorrect. Syphilis is diagnosed via blood tests, not urine.
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